Insomnia is a common sleep problem for adults. The National Institutes of Health estimates that roughly 30 percent of the general population complains of sleep disruption, and approximately 10 percent have associated symptoms of daytime functional impairment consistent with the diagnosis of insomnia. Although many factors contribute to sleep disruption, opioid analgesics, in particular short-acting, are some of the biggest culprits. This week we look at how opioids contribute to sleep disruption and how to avoid the trap of adding sedative-hypnotics to an already high-risk pharmacological soup.